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| Uses |
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| | Ortho-Evra is used to prevent
pregnancy. It contains hormones similar to those in birth control pills. The hormones
release from the patch slowly over time. Using this medication patch does not
protect you or your partner against HIV or other sexually transmitted diseases
(STDs). |  |  |  |
| Directions |
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| | Review the Patient Information
Leaflet. Follow all instructions on how to use this medication patch and also
the best time (during your menstrual cycle) to start using the patch. If any of
the information is unclear, consult your doctor or pharmacist. Open the patch
container and apply one patch to an area of clean, dry skin on the buttock, abdomen,
upper outer arm, or upper body (torso) exactly as directed by your doctor. The
patch is worn for 7 days. Do not apply the patch to the breast(s), the area around
the breast(s); to red, cut, or irritated skin; or over other topical products
(e.g., make-up, creams, lotions, powders). After 7 days, remove the old patch
and apply a new patch. Repeat this weekly cycle for 3 weeks (3 patches equal 1
cycle). After your third patch is removed, you will have one week without using
the patch. Your menstrual cycle (period) usually should start during the week
when you do not use the patch. |  |  |  |
| Side
Effects |
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| | Nausea, vomiting, headache,
redness or itching at the patch application site, dizziness, breast tenderness,
vaginal discomfort/irritation, or stomach cramping/bloating may occur. If any
of these effects persist or worsen, notify your doctor. Promptly tell your doctor
if any of these side effects occur: dark patches on the skin (melasma), change
in appetite, weight changes (gain or loss), problem wearing contact lenses. Tell
your doctor immediately if any of these serious side effects occur: unusual vaginal
discharge, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding,
prolonged or complete stoppage of bleeding), swelling, severe headache, mental/mood
changes. Tell your doctor immediately if any of these unlikely but serious side
effects occur: pain in the groin or lower legs, trouble breathing, rash, chest
pain, stomach pain, vision or eye problems. |  |  |  |
| Precautions |
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| | If you are having surgery,
including dental surgery, tell the doctor or dentist that you are using norelgestromin
and ethinyl estradiol contraceptive patch. Tell your doctor and pharmacist if
you are allergic to estrogens, progestins, or any other medications. Tell your
doctor and pharmacist what prescription and nonprescription medications, vitamins,
and nutritional supplements you are taking. Be sure to mention any of the following:
acetaminophen (APAP, Tylenol); antibiotics; anticoagulants ('blood thinners')
such as warfarin (Coumadin); atorvastatin (Lipitor); clofibrate (Atromid-S); cyclosporine
(Neoral, Sandimmune); griseofulvin (Fulvicin, Grifulvin, Grisactin); HIV protease
inhibitors such as indinavir (Crixivan) and ritonavir (Norvir); medications for
seizures such as carbamazepine (Tegretol), phenobarbital (Luminal, Solfoton),
phenytoin (Dilantin), and topiramate (Topamax); morphine (Kadian, MS Contin, MSIR,
others); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone
(Medrol), prednisone (Deltasone), and prednisolone (Prelone); phenylbutazone;
rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); temazepam (Restoril); theophylline
(Theobid, Theo-Dur); and thyroid medication such as levothyroxine (Levothroid,
Levoxyl, Synthroid). Your doctor may need to change the doses of your medications
or monitor you carefully for side effects. Tell your doctor what herbal products
you are taking, especially products containing St. John's wort. Tell your doctor
if you have or have ever had breast lumps or cancer; endometrial cancer; high
blood pressure; high blood cholesterol and fats; diabetes (high blood sugar);
asthma; stroke; blood clots; toxemia (high blood pressure during pregnancy); heart
attack; epilepsy (seizures); migraine headaches; depression; liver, heart, gallbladder,
or kidney disease; jaundice (yellowing of the skin or eyes); vaginal bleeding
between menstrual periods; and excessive weight gain and fluid retention (bloating)
during the menstrual cycle. Tell your doctor if you are pregnant, plan to become
pregnant, or are breast-feeding. If you become pregnant while using norelgestromin
and ethinyl estradiol contraceptive patch, call your doctor immediately. |
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| Interactions |
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| | Tell your doctor of all prescription
and nonprescription medication you may use, especially: anti-seizure medicine
(e.g., carbamazepine, felbamate, phenobarbital, phenytoin, topiramate), certain
antibiotics (e.g., ampicillin, erythromycin), HIV protease inhibitors (e.g., indinavir,
ritonavir), phenylbutazone, griseofulvin, atorvastatin, azole antifungals (e.g.,
itraconazole, ketoconazole), rifampin, St John's wort, cyclosporine, temazepam,
prednisolone, morphine, theophylline, ascorbic acid (vitamin C), acetaminophen,
aspirin, clofibric acid, modafinil, troglitazone. This product can affect the
results of certain lab tests (e.g., blood tests such as glucose, clotting factors,
or thyroid). Make sure laboratory personnel and your doctors know you use this
product. Do not start or stop any medicine without doctor or pharmacist approval.
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| Missed
Dosages |
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| | If the use of Ortho-Evra is
interrupted (removed or becomes detached) or if you forget to remove this product
at the recommended time, consult your doctor or pharmacist to establish a new
dosing schedule. |  |  |  |
| Storage |
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| | Store Ortho-Evra
patches in their protective pouches at room temperature between 59 and 86 degrees
F (15 and 30 degrees C). Do not refrigerate or freeze. | | | | |
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